The northern territories are characterized by such climatic and geographic factors as climate instability, increased geomagnetic activity, and the contrast of the seasons. In addition, life in an urban environment provokes stressful states of the human body, increasing nervous and emotional stress. Study of changes in the levels of biogenic amines (dopamine, norepinephrine, adrenaline, serotonin) and acetylcholine, as well as hormones of the thyroid and gonads, autoantibodies to thyroid antigens , antisperm antibodies at various levels of psychoemotional stress will help in identifying the mechanisms of development of dysadaptation and pathological changes in the thyroid and reproductive links.