As an alternative to natural and chemically synthesized direct-acting bactericides, it is increasingly used an approach aimed at changing the physiology of a microorganism in order to suppress (reduce) its ability to parasitize and damage biological substrates. In particular, the above said relates to the search and creation of quorum sensing inhibitors in bacteria, they are regarded as an attractive alternative to traditional means of fighting infections, especially those caused by multi-resistant strains of microorganisms. Medicinal plants offer an attractive set of phytochemicals with new potential for microbial disease control due to a spectrum of secondary metabolites present in extracts, which include phenolic compounds, quinones, flavonoids, alkaloids, terpenoids, and polyacetylenes.