Polyfunctional sulfated derivatives of plant polysaccharides with various structures have been synthesized, which are analogs of heparin, a compound traditionally used for anticoagulation treatment.

Compared with the non-fractionated and low-molecular heparins, which are obtained from mammalian tissues and are widely used in clinical practice, the plant polysaccharides-based anticoagulants have the following advantages and features:

• unlimited supply of raw materials;

• the raw material does not contain prion proteins;

• different anticoagulation mechanism.

In cooperation with the Hematology Research Center (Moscow), the Institute of Chemistry has demonstrated that the sulfated derivatives of polysaccharides can be successfully used as an effective means of preventing and treating thrombotic conditions.

Depending on the modification scheme, the proposed polymers exhibit anticoagulant activity to 120.0 U/mg and activity against xanthurenic acid to 40.0 U/mg, and are of low toxicity.