From colon of healthy humans the enterococci strains with marked antimicrobial activity toward gram-positive pathogens, including listeria and staphylococci, have been isolated. The virulence and persistence properties and susceptibility to antibiotics have been determined.

The comparative assessment of current and perspective strains of enterococci according to the spectrum and degree of antagonistic activity has shown that the bacterial cultures, isolated during this study, possess a better pronounced activity in comparison with the known strains cultured abroad (figure).

Cultures may be used as strains of probiotics or probiotic components of synbiotic for development of anti-infective agents.

Anti-listerial activity of enterococci from healthy humans feces in

current study (№ 10 and 18) and known probiotics (№ 23L and 24B)

Indicator strains: 1 – Listeria ivanovii, 2 – L. innocua, 3 – L. seeligeri,

4 – L. monocytogenes.